The aerobic fed-batch production of recombinant human growth hormone (rhGH) by Escherichia coli was studied. The goal was to determine the production and protein degradation pattern of this product during fed-batch cultivation and to what extent scale differences depend on the presence of a fed-batc
Effect of surfactants on the physical stability of recombinant human growth hormone
β Scribed by Manohar Katakam; Leonard N. Bell; Ajay K. Banga
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 478 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0022-3549
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## Abstract We have performed a detailed characterization of recombinant human growth hormone that included the identification of the entire sequence with disulfide linkages as well as subtle modifications by a sensitive liquid chromatography coupled online with tandem mass spectrometry (LCβMS) app