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Effect of sulfobromophthalein on biliary excretion of taurocholate and pravastatin in bile duct-ligated rat

✍ Scribed by Hajime Takikawa; Naoyo Sano; Akihiro Sato; Masami Yamanaka

Book ID
114303899
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
337 KB
Volume
6
Category
Article
ISSN
0928-4346

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In an earlier study we showed that bile duct-ligated rats were highly susceptible to gentamicin nephrotoxicity and that oral calcium administration had a pronounced protective effect. The mechanism by which this occurs is unclear. Because cations compete with gentamicin for tubule binding sites, it