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Effect of substrates on reconstitution of the mitochondrial respiratory chain under various conditions

✍ Scribed by V.N. Luzikov; M.M. Rakhimov; I.V. Berezin

Book ID
115715106
Publisher
Elsevier Science
Year
1969
Tongue
English
Weight
691 KB
Volume
180
Category
Article
ISSN
0005-2728

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## Abstract Cyclosporin A (CyA), a potent immunosuppressant, was used to determine the hepatotoxic effect in long‐term treatments. Male Wistar rats were used in these experiments. They were given CyA chronically at doses used in patients for 120 days, and at doses of 5, 10, 15 and 20 mg kg^βˆ’1^ day^