Effect of substance P on neuronal activity in the antinociceptive system
β Scribed by G. N. Kryzhanovskii; S. I. Igon'kina; V. V. Trubetskaya; P. Oehme; J. Odarjuk
- Publisher
- Springer US
- Year
- 1989
- Tongue
- English
- Weight
- 310 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0007-4888
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Experiments have been conducted to examine the effect of chronic administration of bromoxynil, Β―uroxipir and bensultap on the in-vitro seizure susceptibility (induced by 4-aminopyridine) and excitability of neocortical slices of rat brain. The treatment regimes were (A) administration of spray solut
Substance P (SP) acts as a neurotransmitter in the neostriatum through the axon collaterals of spiny projection neurons. However, possible direct or indirect actions of SP on the neostriatal output neurons have not been described. Targets of SP terminals within the neostriatum include interneurons,