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Effect of Structural Modifications on the Activity of the Leadzyme †

✍ Scribed by Chartrand, Pascal; Usman, Nassim; Cedergren, Robert

Book ID
126428516
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
262 KB
Volume
36
Category
Article
ISSN
0006-2960

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✍ Jefferies, Phillip R.; Yu, Pauline; Casida, John E. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 302 KB 👁 2 views

The toxicity of ryanodine (1) and 9,21-didehydroryanodine (2) (the principal active ingredients of the botanical insecticide ryania) to adult female house Ñies (Musca domestica L.) is attributable to binding to the ryanodine receptor (ryr) and thereby disrupting the Ca2`-release channel. These ryano