Effect of stress on choline acetyltransferase activity of the brain and the adrenal of the rat
β Scribed by Z. Z. Wahba; K. F. A. Soliman
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 427 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1420-682X
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Caracemide was found to inhibit choline acetyltransferase (CAT) from rat brain. A concentration of 0.5 mM caracemide inhibited the enzyme by 93%, whereas a degradation product from caracemide, N-(methylcarbamoyloxy)acetamide, produced only a 50% inhibition. Two other degradation products, N-(methyl-
Using microdissection and quantitative microassay, choline acetyltransferase (ChAT) activity was mapped in the cochlear nucleus (CN) and in the source nuclei of the olivocochlear bundle, the lateral superior olive and ventral nucleus of the trapezoid body. In control rats, gradients of ChAT activity