Bladder outlet obstruction induces severe changes in urinary bladder function and metabolism. These changes are characterized by significant reductions in the ability of the in vitro whole bladder to generate pressure and to empty. Metabolically, partial outlet obstruction induces a shift from oxida
Effect of partial outlet obstruction on choline acetyltransferase activity in the rat and rabbit
β Scribed by Robert M. Levin; Masahiko Saito; Alan J. Wein; David Packard; Adam Cohen; Niels Haugaard
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 462 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0733-2467
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## Abstract ## Objectives Bladder outlet obstruction has shown to damage detrusor mitochondria with impaired detrusor contractility. One likely cause for mitochondrial injury is reactive oxygen species (ROS)βinduced damages, including lipid peroxidation injury. We designed this study to examine th
Using microdissection and quantitative microassay, choline acetyltransferase (ChAT) activity was mapped in the cochlear nucleus (CN) and in the source nuclei of the olivocochlear bundle, the lateral superior olive and ventral nucleus of the trapezoid body. In control rats, gradients of ChAT activity