Effect of specific growth limitations on cell wall composition ofStaphylococcus aureusH
β Scribed by Bryan C. Dobson; A. Ronald Archibald
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 644 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0302-8933
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β¦ Synopsis
Conditions are described for the continuous culture of a derivative of Staphylococcus aureus H in a fully defined minimal medium in which cysteine is the sole amino acid. The effects of grewth under various nutrient limitations on the composition and properties of the cell wall have been studied. The proportion of ribitol teichoic acid present in the wall, and the extent to which it is substituted with N-acetylglucosamine, varies in bacteria grown under different conditions as does the composition and extent of cross-linking of the peptidoglycan. Neither the derivative nor the original strain H produced teichuronic acid when grown under phosphate limitation.
π SIMILAR VOLUMES
Mice irradiated with lethal doses of total body X-irradiation are very susceptible to Staphylococcus aureus. A difference in virulence between a "mousevirulent" strain and a "mouse-non-virulent" strain which lacks cell-wall aggressin could nevertheless be demonstrated. The virulence of the "mouse-no