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Effect of some petroleum sulfonate surfactants on the apparent water solubility of organic compounds

✍ Scribed by Kile, Daniel E.; Chiou, Cary T.; Helburn, Robin S.

Book ID
125488343
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
561 KB
Volume
24
Category
Article
ISSN
0013-936X

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A new approach of improving drug dissolution properties is described. This method exploits the property of a carrier owing to the hydrotalcite-type anionic clays (HTlc). HTlc is an inorganic layered solid that lodges anionic compounds among its layers. As HTlc dissolves at acidic pH values (pH < 4),