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Effect of some monohydric alcohols on the functional stability of bovine liver β-galactosidase

✍ Scribed by Lorenzo Cordone; Vincenzo Izzo; Giuseppe Sgroi; Sandro L. Fornili

Publisher
Wiley (John Wiley & Sons)
Year
1979
Tongue
English
Weight
499 KB
Volume
18
Category
Article
ISSN
0006-3525

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✦ Synopsis

Abstract

We report on experiments showing that the presence of some monohydric alcohols in the solution medium perturbs the kinetics of bovine liver β‐galactosidase. The effect increases with increasing alcohol concentration and alkyl group size. To explain this effect we suggest a model that considers the existence of functional and nonfunctional enzyme conformations in thermodynamical equilibrium. This equilibrium is dependent both on alcohol concentration and on alkyl group size.

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Effect of some monohydric alcohols on the oxygen affinity of hemoglobin: Relevance of solvent dielectric constant and hydrophobicity
✍ Lorenzo Cordone; Antonio Cupane; Pier L. San Biagio; Eugenio Vitrano 📂 Article 📅 1979 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 644 KB

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✍ Lorenzo Cordone; Antonio Cupane; Pier L. San Biagio; Eugenio Vitrano 📂 Article 📅 1981 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 527 KB

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