Effect of sodium valproate on mania
✍ Scribed by H. M. Emrich; D. Zerssen; W. Kissling; H. -J. Möller; A. Windorfer
- Publisher
- Springer-Verlag
- Year
- 1980
- Tongue
- English
- Weight
- 989 KB
- Volume
- 229
- Category
- Article
- ISSN
- 1433-8491
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A mentally retarded 23-year-old woman with myoclonic astatic epilepsy developed an abnormal posture of extreme forward flexion, called camptocormia, during valproate monotherapy. Camptocormia occurred concomitantly with an increase of the plasma valproate level from about 330 mumol/l up to 530 mumol
Sodium valproate is an anticonvulsant which elevates GABA levels in the brain. GABA interacts with dopamine functionally in certain areas of the brain involved in motor behavior such as the nucleus accumbens and the substantia nigra. In order to determine whether GABA can play a functional role in t