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Effect of GABA-acting drugs diazepam and sodium valproate on thermoregulation in rats

โœ Scribed by Rumen Nikolov; Krassimira Yakimova

Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
298 KB
Volume
33
Category
Article
ISSN
0306-4565

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The distribution of VPA has been investigated in several brain areas of the rat, and GABA increases were measured. A biphasic exponential decay was observed for VPA; the slowest decrease was noted in the olfactory bulbs and in the hypothalamus where GAD and GABA-T activities were the highest. The da