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Effect of single doses of cimetidine and ranitidine on the steady-state plasma levels of midazolam

โœ Scribed by Klotz, Ulrich; Arvela, Pentti; Rosenkranz, Bernd


Book ID
109843756
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
301 KB
Volume
38
Category
Article
ISSN
0009-9236

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The disposition of theophylline was studied on four occasions in eight healthy adult males. The control mean theophylline half-life and clearance were 7.32 h and 086 ml min-Ikg-', respectively. After 5 days pretreatment with placebo the corresponding values of 7.01 and 0-88 were not significantly di