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Effect of single and repeated doses of acrylamide and bis-acrylamide on glutathione-S-transferase and dopamine receptors in rat brain

โœ Scribed by Sriprakash Srivastava; Mohammad I. Sabri; Ashok K. Agrawal; Prahlad K. Seth

Book ID
118871390
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
396 KB
Volume
371
Category
Article
ISSN
0006-8993

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## Abstract The toxicity of dietary acrylamide (AA) depends on its biotransformation pathways, in which phase I cytochrome Pโ€450 enzymes transform AA into glycidamide. The phase II enzyme glutathione\___S__\_transferase (GST) catalyses the conjugation of AA with glutathione (GSH). GST induction by