The effect of rifampicin and pyrazinamid
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Helen M. Baldan; Helene J. De Rosa; Iguatemy L. Brunetti; Valdecir F. Ximenes; R
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Article
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2007
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John Wiley and Sons
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English
β 99 KB
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Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo