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Effect of Silibinin on the Pharmacokinetics of Pyrazinamide and Pyrazinoic Acid in Rats

✍ Scribed by Wu, J.-W.; Tsai, T.-H.


Book ID
126987053
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2007
Tongue
English
Weight
369 KB
Volume
35
Category
Article
ISSN
0090-9556

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The effect of rifampicin and pyrazinamid
✍ Helen M. Baldan; Helene J. De Rosa; Iguatemy L. Brunetti; Valdecir F. Ximenes; R πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 99 KB πŸ‘ 2 views

Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo