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Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes

✍ Scribed by Jigar P. Patel; Dalia A. Hamdy; A. O. El-kadi; Dion R. Brocks


Book ID
112049484
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
873 KB
Volume
24
Category
Article
ISSN
0899-0042

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The effect of hyperlipidemia on the biodistribution of (+/-)-halofantrine (HF) was studied in rats. Plasma, adipose, and highly perfused tissues heart, lung, liver, kidney, spleen and brain were harvested for up to 48 h after dosing animals with 2 mg/kg (+/-)-HF intravenously by tail vein. Stereospe

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