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Effect of self-aggregation of γ-cyclodextrin on drug solubilization

✍ Scribed by Phatsawee Jansook; Maria D. Moya-Ortega; Thorsteinn Loftsson


Book ID
106389413
Publisher
Springer Netherlands
Year
2010
Tongue
English
Weight
272 KB
Volume
68
Category
Article
ISSN
0923-0750

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Self-association and cyclodextrin solubi
✍ Thorsteinn Loftsson; Auður Magnúsdóttir; Már Másson; Jóhanna F. Sigurjónsdóttir 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 141 KB

Phase-solubility diagrams are frequently used to calculate stoichiometry of drug/cyclodextrin complexes. Linear diagrams (A(L)-type systems) are thought to indicate that the complexes are first order with respect to cyclodextrin and first or higher order with respect to the drug. Positive deviation