𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Combined effect of cosolvent and cyclodextrin on solubilization of nonpolar drugs

✍ Scribed by Ping Li; Luwei Zhao; Samuel H. Yalkowsky

Book ID
109389298
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
75 KB
Volume
88
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Solubilization behavior of poorly solubl
Solubilization behavior of poorly soluble drugs with combined use of Gelucire 44/14 and cosolvent
✍ Kohsaku Kawakami; Kyoko Miyoshi; Yasuo Ida πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 140 KB

Gelucire 44/14 is a surface-active excipient that can solubilize poorly soluble drugs. We investigated its solubilization behavior when coexisting with dimethylacetoamide (DMA) or dimethylsulfoxide (DMSO), both of which are also expected to enhance drug solubility. Gelucire was confirmed to form mic

Self-association and cyclodextrin solubi
Self-association and cyclodextrin solubilization of drugs
✍ Thorsteinn Loftsson; AuΓ°ur MagnΓΊsdΓ³ttir; MΓ‘r MΓ‘sson; JΓ³hanna F. SigurjΓ³nsdΓ³ttir πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 141 KB

Phase-solubility diagrams are frequently used to calculate stoichiometry of drug/cyclodextrin complexes. Linear diagrams (A(L)-type systems) are thought to indicate that the complexes are first order with respect to cyclodextrin and first or higher order with respect to the drug. Positive deviation