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Effect of selected inhibitors on growth, pigmentation, and aflatoxin production byAspergillus parasiticus

โœ Scribed by Raul Valcarcel; J. W. Bennett; Joanne Vitanza

Publisher
Springer Netherlands
Year
1986
Tongue
English
Weight
325 KB
Volume
94
Category
Article
ISSN
0301-486X

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โœฆ Synopsis

We have treated a wild type strain of Aspergillus parasiticus with several known aflatoxin inhibitors in hopes of finding specific metabolic blocks in the aflatoxin biosynthetic pathway. In defined medium, benzoic acid (2 and 3 mg/ml), cinnamon (1 mg/ml), and sodium acetate (5 mg/ml) were fungitoxic. Benzoic acid (0.5 and 1 mg/ml), chlorox (5 ~l/ml), and dimethyl sulfoxide (5 ~l/ml) did not affect dry weight or mycelial pigmentation. Sodium benzoate (1, 2, 4 and 8 mg/ml) added after 2 days growth inhibited aflatoxin production in two defined media. We were unable to confirm previously published reports that an uncharacterized yellow pigment accumulates with benzoate-inhibition of aflatoxin biosynthesis.

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Effect of acetone on production of aflat
Effect of acetone on production of aflatoxins and versicolorin pigments by resting cell cultures of aspergillus parasiticus
โœ J. W. Bennett; L. S. Lee; G. G. Gaar ๐Ÿ“‚ Article ๐Ÿ“… 1976 ๐Ÿ› Springer Netherlands ๐ŸŒ English โš– 354 KB

Resting cell cultures of Aspergillus parasiticus were grown in medium containing four different concentrations of glucose, with and without acetone. In addition, the effect of different equimolar concentrations of acetone, acetic acid, ethanol, and sodium acetate was compared at two glucose levels.