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Effect of route of administration on the pharmacokinetics and toxicokinetics of cinnarizine in dogs

โœ Scribed by Bao-qiu Li; Gui-qin Yang; Shi-hong Fang; Ji-you Gao; Fang-min Gu; Xin Dong; Jian-xin Zhang; Yong Wang

Book ID
113592289
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
279 KB
Volume
40
Category
Article
ISSN
0928-0987

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๐Ÿ“œ SIMILAR VOLUMES

Effect of cinnarizine on peripheral circ
Effect of cinnarizine on peripheral circulation in dogs
โœ J.M. Van Nueten; P.A.J. Janssen ๐Ÿ“‚ Article ๐Ÿ“… 1972 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 249 KB

The effectiveness of cinnarizine on the peripheral vascular system was evaluated on the perfused hind leg of the anesthetized dog. Cinnarizine is a potent inhibitor of 1-norepinephrine-induced vasoconstriction. It decreased peripheral resistance in the vascular bed of the hind leg but did not change