Effect of Recombinant Human D-Factor on the Growth of Leukemic Blast Progenitors from Acute Myeloblastic Leukemia Patients
β Scribed by Chen, Guan-Jin ;Tomida, Mikio ;Hozumi, Motoo ;Nara, Nobuo
- Book ID
- 108579604
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1992
- Tongue
- English
- Weight
- 332 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0910-5050
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π SIMILAR VOLUMES
Recombinant hemopoietic colony-stimulating factors (CSFs), including GM-CSF, G-CSF and IL-3, have been shown to be effective stimulators of both self-renewal and terminal differentiation of blast stem cells in acute myeloblastic leukemia (AML). We have examined the activity of a fourth growth factor
## Abstract We have studied the effect of recombinant human Stem Cell Factor (SCF) on the growth of human peripheral blood, bone marrow, and cord blood progenitor cells in semisolid medium. While SCF alone had little colonyβstimulating activity under fetal bovine serum (FBS)βdeprived culture condit