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Effect of Rapamycin on TGF-β1-induced epithelial-mesenchymal transition in LoVo colonic adenocarcinoma cells

✍ Scribed by Renhu Sun; Jiang Li; Jing Cui; Qing Lv; Xinghua Liu; Guobin Wang

Book ID
117696628
Publisher
Chinese Electronic Periodical Services
Year
2009
Tongue
English
Weight
370 KB
Volume
23
Category
Article
ISSN
1007-4376

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## Abstract Idiopathic pulmonary fibrosis is characterized by myofibroblast accumulation, extracellular matrix (ECM) remodeling, and excessive collagen deposition. ECM‐producing myofibroblasts may originate from epithelial cells through epithelial to mesenchymal transition (EMT). TGF‐β1 is an induc