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Effect of pyridoxine on tumor necrosis factor activitiesin vitro

✍ Scribed by Eva Hofsli; Anders Waage

Publisher
Springer
Year
1992
Tongue
English
Weight
516 KB
Volume
5
Category
Article
ISSN
0921-299X

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The ability of recombinant human tumor necrosis factor (rH-TNF-alpha) to induce regression of sarcoma 180 in vivo was evaluated. The tumor was cured by TNF in the course of 4 weeks. TNF inhibited proliferation of sarcoma 180 cells in vitro, which suggests a direct effect of TNF on tumor cells in viv