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Effect of PSC 833, a potent inhibitor of P-glycoprotein, on the growth of astrocytoma cells in vitro

✍ Scribed by V Sadanand; J Kankesan; A Yusuf; C Stewart; J.T Rutka; J.J Thiessen; V Ling; P.M Rao; S Rajalakshmi; D.S.R Sarma


Book ID
117467836
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
248 KB
Volume
198
Category
Article
ISSN
0304-3835

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Oxycodone pharmacokinetics and pharmacod
✍ Emma BostrΓΆm; Ulrika S.H. Simonsson; Margareta Hammarlund-Udenaes πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 93 KB

The objective of this study was to investigate the in vivo influence of the P-glycoprotein (P-gp) inhibitor PSC833 on the plasma pharmacokinetics, total brain concentrations and tail-flick latency of oxycodone in rats. Eight rats each received an infusion of PSC833 or vehicle without PSC833. One hou