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Effect of protein synthesis inhibitors and low concentrations of actinomycin D on ribosomal RNA synthesis

✍ Scribed by Silvia Iapalucci-Espinoza; María Teresa Franze-Fernández


Book ID
115909625
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
356 KB
Volume
107
Category
Article
ISSN
0014-5793

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## Abstract Actinomycin D and α‐amanitin (an inhibitor of RNA polymerase II) were used to determine the effect of inhibiting RNA synthesis during pre‐implantation mouse embryogenesis. Actinomycin D (0.01 μg/ml) was an effective inhibitor of blastulation and of cleavage from the 1 cell stage on. The