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Effect of protein kinase inhibitors on ACTH-stimulated aldosterone production in rat zona glomerulosa cells

โœ Scribed by Doris Kurscheid-Reich; Lutz Hegemann; Stefan Wohlfeil

Book ID
118345701
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
385 KB
Volume
51
Category
Article
ISSN
0024-3205

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Acute effects and action mechanisms of prolactin (PRL) on aldosterone secretion in zona glomerulosa (ZG) cells were investigated in ovariectomized rats. Administration of ovine PRL (oPRL) increased aldosterone secretion in a dose-dependent manner. Incubation of [3H]-pregnenolone combined with oPRL i