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Effect of ACTH on biosynthesis of aldosterone and corticosterone by monolayer cultures of rat adrenal zona glomerulosa cells

โœ Scribed by Peter J. Hornsby; Michael J. O'Hare; A. Munro Neville


Book ID
118854348
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
317 KB
Volume
54
Category
Article
ISSN
0006-291X

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Acute effects and action mechanisms of prolactin (PRL) on aldosterone secretion in zona glomerulosa (ZG) cells were investigated in ovariectomized rats. Administration of ovine PRL (oPRL) increased aldosterone secretion in a dose-dependent manner. Incubation of [3H]-pregnenolone combined with oPRL i