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Effect of plasma protein and tissue binding on the time course of drug concentration in plasma

✍ Scribed by Patrick J. McNamara; Gerhard Levy; Milo Gibaldi


Book ID
112472503
Publisher
Springer
Year
1979
Tongue
English
Weight
582 KB
Volume
7
Category
Article
ISSN
1573-8744

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The aim of this work was to provide a short overview of existing methods for the determination of free drug concentration and protein-drug binding fraction in plasma. Various methods have been described in terms of principles, evaluation of methods, and applications in recent years, with an emphasis