Effect of photofrin II and light energy on retinoblastoma-like cells in vitro
โ Scribed by Jens Winther
- Book ID
- 112293943
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 538 KB
- Volume
- 115
- Category
- Article
- ISSN
- 1432-1335
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Retinoblastoma (Rb) is the most common intraocular tumor of childhood and has been demonstrated clinically to be very sensitive to external beam radiation (EBR). The purpose of this study was to determine the survival of Rb cell lines at different endpoints following irradiation. We also studied Rb-
## Abstract DBA mice bearing CaD~2~ mammary carcinomas were used to determine the effect of giving small doses of light to the tumor area 1.5 hr after injecting Photofrin II (PII). The smallest light dose applied (12.5 J/cm^2^) had no effect on the uptake of Pll in the tumor and its surrounding tis