Effect of phosphatidylcholine vesicles on the activity of DNA polymerase-α

✍ Scribed by S. Capitani; G. Mazzotti; R. Jovine; S. Papa; N. M. Maraldi; F. A. Manzoli

• Book ID: 104668153
• Publisher: Springer
• Year: 1979
• Tongue: English
• Weight: 263 KB
• Volume: 27
• Category: Article
• ISSN: 0300-8177
• DOI: 10.1007/bf00215361

✦ Synopsis

Phosphatidylcholine vesicles stimulate the activity of the DNA polymerase-alpha from calf thymus. This effect is dependent upon the way of addition to the Mg ions, and the extent of the 3H-dTTP incorporation is closely related to the concentration of the vesicles. A role of phospholipids on the activity of the DNA-related enzymes is suggested.