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Effect of molecular crowding on DNA polymerase activity

✍ Scribed by Yoshiharu Sasaki; Daisuke Miyoshi; Direktor Naoki Sugimoto


Book ID
112011137
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
229 KB
Volume
1
Category
Article
ISSN
1860-6768

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Phosphatidylcholine vesicles stimulate the activity of the DNA polymerase-alpha from calf thymus. This effect is dependent upon the way of addition to the Mg ions, and the extent of the 3H-dTTP incorporation is closely related to the concentration of the vesicles. A role of phospholipids on the acti