Enzymes of the glutathione-dependent detoxification pathway (glutathione S-transferase and y-glutamyltranspeptidase) I) were induced, and the glutathione pool was completely depleted by phenoxyacetic acid in Penicillium chrysogenum mycelia incubated for 15 h in a culture medium containing lactose as
Effect of phenoxyacetic acid on the glutathione metabolism of Penicillium chrysogenum
✍ Scribed by Tamás Emri; Éva Leiter; István Pócsi
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 152 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0233-111X
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Physiological effects of phenoxyacetic acid, the penicillin V side-chain precursor, on steady-state continuous cultures of Penicillium chrysogenum have been studied both theoretically and experimentally. Theoretical calculations show that at an extracellular pH of 6.50, phenoxyacetic acid has neglig
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