Bioavailability and in vivo release beha
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Kengo Ikegami; Kozo Tagawa; Takashi Osawa
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Article
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2006
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John Wiley and Sons
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English
β 131 KB
To determine the usefulness of monkey as an animal model, bioavailability and in vivo release behaviors of theophylline (TP) after oral administration of controlled-release beads in dogs, monkeys, and minipigs were evaluated. Controlled-release beads were prepared using a centrifugal-fluid type gran