𝔖 Bobbio Scriptorium
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Effect of ph on the in vitro dissolution and in vivo absorption of controlled-release theophylline in dogs

✍ Scribed by Vijay I. Vashi; Marvin C. Meyer


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
554 KB
Volume
77
Category
Article
ISSN
0022-3549

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To determine the usefulness of monkey as an animal model, bioavailability and in vivo release behaviors of theophylline (TP) after oral administration of controlled-release beads in dogs, monkeys, and minipigs were evaluated. Controlled-release beads were prepared using a centrifugal-fluid type gran