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Effect of pH, mucin and bovine serum on rifampicin permeability through Caco-2 cells

✍ Scribed by José Eduardo Gonçalves; Mariane Ballerini Fernandes; Chang Chiann; Maria Nella Gai; Jacqueline De Souza; Sílvia Storpirtis

Book ID
115550723
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
153 KB
Volume
33
Category
Article
ISSN
0142-2782

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Tetrazole compounds: The effect of struc
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✍ Amber M. Young; Kenneth L. Audus; John Proudfoot; Mehran Yazdanian 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB 👁 1 views

A tetrazole ring is often used in drug discovery as a replacement for the carboxylic acid group. Previous work indicates that compounds containing a tetrazole moiety show asymmetric permeability in Caco-2 cells characteristic of an efflux transporter substrate. The aim of this study is to determine