Effect of PEGylation on stability of peptide in poly(lactide-co-glycolide) microspheres
โ Scribed by Eun Ji Park; Tae Hyuk Tak; Dong Hee Na; Kang Choon Lee
- Book ID
- 107642293
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 528 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0253-6269
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People's Republic of China SYNOPSIS Polylactide (PLA) and poly (lactide-co-glycolide) (PLGA) were prepared by bulk ringopening polymerization of lactide or lactide/glycolide using stannous octoate as initiator. PLA and PLGA microspheres with an average diameter of 65-100 pm were prepared by a solven
A formaldehyde-mediated aggregation pathway (FMAP) has been shown to be primarily responsible for the solid-state aggregation of lyophilized formalinized protein antigens [e.g., tetanus toxoid (TT) and formalinized bovine serum albumin (f-BSA)] in the presence of moisture and physiological temperatu