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Physical Aging of Progesterone-Loaded Poly(D,L,-lactide-co-glycolide) Microspheres

✍ Scribed by V. Rosilio; M. Deyme; J. P. Benoit; G. Madelmont


Book ID
110308439
Publisher
Springer US
Year
1998
Tongue
English
Weight
438 KB
Volume
15
Category
Article
ISSN
0724-8741

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A physicochemical study of the morpholog
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Progesterone-loaded microspheres are fabricated by a solvent evaporation process from a poly(D,L-lactide-co-glycolide) (85/15 PLG) and from a-progesterone. Methylene chloride is used as solvent and polyvinyl alcohol and methylcellulose are used as surfactants. The microspheres are characterized by s

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Ketotifen (KT) was encapsulated into poly(D,L-lactide) (PLA) and poly(D,Llactide-co-glycolide) (PLGA 50/50) by spray-drying to investigate the use of biodegradable drug-loaded microspheres as delivery systems in the intraperitoneal cavity. Ketotifen stability was evaluated by HPLC, and degradation w