Effect of partial outlet obstruction of the rat urinary bladder on the response to alterations in the concentrations of potassium and calcium
β Scribed by Masahiko Saito; Alan J. Wein; Robert M. Levin
- Book ID
- 113328226
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 553 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0306-3623
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## Abstract ## Aim To determine if tamsulosin treatment prevents or decreases the incidence and severity of outlet obstructionβinduced bladder dysfunction in rabbits. ## Materials and Methods Male New Zealand White rabbits were treated with tamsulosin or vehicle for 4 weeks with treatments initi
Bladder outlet obstruction induces severe changes in urinary bladder function and metabolism. These changes are characterized by significant reductions in the ability of the in vitro whole bladder to generate pressure and to empty. Metabolically, partial outlet obstruction induces a shift from oxida