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Effect of PABA on Chloroquine Resistance in Plasmodium berghei yoelii

✍ Scribed by CARTER, RICHARD


Book ID
109682856
Publisher
Nature Publishing Group
Year
1972
Tongue
English
Weight
240 KB
Volume
238
Category
Article
ISSN
0028-0836

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A new series of 6-(4 0 -aryloxy-phenyl)vinyl-1,2,4-trioxanes 10a-d, 11a-d, and 12a-d have been synthesized and evaluated for their antimalarial activity against multidrug-resistant Plasmodium yoelii in Swiss mice by oral route. Trioxanes 10b and 10c, the two most active compounds of the series, prov