✦ LIBER ✦

Effect of ovariectomy on magnetic resonance T2* in rat femur

✍ Scribed by David Checkley; Andrew J. Millest; Donna Johnstone; John C. Waterton

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 475 KB
Volume: 36
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910360411

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Measurements have been made in the rat femur in vivo and ex vivo by using an asymmetric spin echo technique of T~2′~, the susceptibility contribution to T~2~*. The trabecular spacing in this study in rat bone is considerably less than in previous studies in the human. A significant increase in T~2′~ was seen in vivo 3 mm proximal to the growth plate with ovariectomy (a model of osteopenia), from 8.1 ± 0.7 to 10.0 ± 0.6 ms. Parallel changes in trabecular bone mineral density measured by quantitative computed tomography were found. T~2′~ was higher in living bones than in the same bones measured post mortem.

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