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Effect of oral contraceptives on the transport of chlorpromazine across the CACO-2 intestinal epithelial cell line

✍ Scribed by Deon Brown; Theunis C Goosen; Mano Chetty; Josias H Hamman

Book ID
117639505
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
337 KB
Volume
56
Category
Article
ISSN
0939-6411

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Transport of levovirin prodrugs in the h
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✍ Fujun Li; Lei Hong; Cheng-I Mau; Rebecca Chan; Than Hendricks; Chuck Dvorak; Cal πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 142 KB πŸ‘ 1 views

The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi