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Effect of oral contraception on water-suppressed proton NMR spectra of plasma

✍ Scribed by Pierre G. Carlier; Francis Vaesen; Raymond G. Gilles; Elisabeth A. Fradin; Georges L. Rorive


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
282 KB
Volume
17
Category
Article
ISSN
0740-3194

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✦ Synopsis


Lipid linewidths were measured in the plasma proton spectra of young women. The individuals taking a contraceptive pill associating ethinyloestradiol and levonorgestrel or norethisterone were found with an average linewidth 2.5 Hz narrower than controls. As this drug regimen systematically induces an increase in plasma VLDL and a decrease in HDL/LDL ratio, our observation supports the theory that the Fossel test reflects plasma lipids abnormalities in cancer patients.


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