𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of aging and diet on proton NMR spectra of rat urine

✍ Scribed by J. D. Bell; P. J. Sadler; V. C. Morris; O. A. Levander

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
477 KB
Volume
17
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

500 MHz 1H NMR studies of rat urine are used to assess metabolic changes resulting from aging (0.5-20 months) and changes in diet (casein versus chow). Aging rats fed chow diets decrease their excretion of citrate and 2-oxoglutarate, while the output of taurine and creatinine increases. Only young rats (1 month or less postweaning) excrete significant amounts of betaine and trimethylamine-N-oxide. Rats fed casein diets for 1 month postweaning do not excrete 2-oxoglutarate and excrete lower levels of hippurate, succinate, and citrate compared to rats fed chow diets. They also excrete N-methylnicotinamide. These high resolution proton NMR studies provide metabolic profiles which are not readily available by other techniques.

πŸ“œ SIMILAR VOLUMES

Effect of soft diet and aging on rat mas
Effect of soft diet and aging on rat masseter muscle and its motoneuron
✍ Miyata, Hirofumi ;Sugiura, Takao ;Kawai, Yosuke ;Shigenaga, Yoshio πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 651 KB

To determine the effect of a soft diet and aging on the masticatory motor unit, we investigated the morphologic and metabolic properties of the superficial masseter muscle and its motoneurons in rats. Twenty rats were divided into four groups of five rats: rats fed a hard diet until 4 months after b

Substituent effect in aromatic proton NM
Substituent effect in aromatic proton NMR spectraβ€”IV Proton NMR spectra of monosubstituted (poly) methylbenzenes
✍ Yujiro Nomura; Yoshito Takeuchi πŸ“‚ Article πŸ“… 1969 πŸ› John Wiley and Sons 🌐 English βš– 728 KB

Proton N M R spectra of ]-substituted 2,4-dimethylbcnzenes (2). I-substituted 2.6dimethylbenzenes (3) and 1-substituted 2,4,6-trimethylbenzenes (4) were determined and the SCS values compared with those of monosubstituted benzenes (1). SCS of 1 are assumed to be primarily due to the effects of x-ele

Effect of oral contraception on water-su
Effect of oral contraception on water-suppressed proton NMR spectra of plasma
✍ Pierre G. Carlier; Francis Vaesen; Raymond G. Gilles; Elisabeth A. Fradin; Georg πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 282 KB

Lipid linewidths were measured in the plasma proton spectra of young women. The individuals taking a contraceptive pill associating ethinyloestradiol and levonorgestrel or norethisterone were found with an average linewidth 2.5 Hz narrower than controls. As this drug regimen systematically induces a

The effect of sample freezing on proton
The effect of sample freezing on proton magic-angle spinning NMR spectra of biological tissue
✍ David A. Middleton; Daniel P. Bradley; Susan C. Connor; Paul G. Mullins; David G πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 382 KB

## Abstract Magic‐angle spinning (MAS) has recently been shown to enhance spectral resolution in NMR examinations of intact biological tissue ex vivo. This work demonstrates that freezing certain tissue samples before examination by ^1^H MAS NMR can have a marked effect on their spectra. Spectra of