Effect of Oral Activated Charcoal on the Pharmacokinetics of Quinidine and Quinine Administered Intravenously to Rabbits
β Scribed by Hasan, Mazen M. ;Hassan, Mohammad A. ;Rawashdeh, Nayel M.
- Book ID
- 114801469
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 426 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0901-9928
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Plasma. concentrations of quinine were measured by high-performance liquid chromatography (HPLC) after oral administration of 250, 500 and 1000 mg base to seven healthy adults. The doses were administered after an overnight fast. A washout period of at least 21 days was allowed between the doses. Ar
The effect of orally administered activated charcoal (AC) on the sleep times of mice following intravenous injection of various hypnotics was investigated. Preliminary studies with phenobarbital (Pb) showed that a linear relationship exists between the Pb-induced sleep time and the logarithm of the