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Effect of nonsense mutations on PTEN mRNA stability

✍ Scribed by Anthony M. Raizis; Martin M. Ferguson; Peter M. George


Book ID
106136331
Publisher
Springer
Year
2000
Tongue
English
Weight
83 KB
Volume
107
Category
Article
ISSN
0340-6717

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The genetic map of 27 mutants of the URA1 yeast gene has been established by meiotic recombination and 16 nonsense mutations characterized. The half life of URA1 mRNA was determined by two independent methods in the wild-type and in two ochre mutants localized at each extremity of the genetic map. A