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Effect of nicotine cessation on the central serotonergic systems in mice: involvement of 5-HT2receptors

✍ Scribed by Kayo Yasuda; Katsuya Suemaru; Hiroaki Araki; Yutaka Gomita


Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
105 KB
Volume
366
Category
Article
ISSN
0028-1298

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The effects of a 5-HT1receptor ligand is
✍ G. M. Goodwin; Rosemarie J. Souza; A. R. Green πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 557 KB

The effects of 2-(4-(4-(2-pyrimidinyl)-l-piperazinyl)-butyl)-1,2-benzoisothiazol-3(2H)one-1,1-dioxide hydrochloride (isapirone, TVX Q 7821), a putative 5-HT1 receptor antagonist, has been studied on various models of 5-HT receptor sub-type function. In mice TVX Q 7821 produced a dose-dependent inhib