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Effect of multiple treatments with 5-fluorouracil on the micronucleus test

โœ Scribed by A. Ohuchida; A. Furukawa; S. Umeno; H. Tamura; N. Horiya; T. Hara; M. Katoh; T. Shibuya


Book ID
113252379
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
169 KB
Volume
252
Category
Article
ISSN
0165-1161

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The thymidine labelling index and the mitosis rate (blocked by colcemid) in the basal cell layer of the guinea pig were determined before and during treatment with 5-fluorouracil (1 mg i.p. in 2 day's interval/100 g body weight). Additionally, the epidermal area and thickness and the number and size