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Effect of mitomycin C and rubomycin C on nucleic acid metabolism in the rat liver

โœ Scribed by A. A. Pokrovskii; A. L. Pozdnyakov; L. V. Kravchenko; N. N. Kasatkina; V. A. Tutel'yan

Publisher
Springer US
Year
1972
Tongue
English
Weight
256 KB
Volume
73
Category
Article
ISSN
0007-4888

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To evaluate the effects of anaerobic conditions and inducers for the mixed-function oxidase system on the metabolism of mitomycin C, a bioreductive alkylating agent widely used for the treatment of hepatocellular carcinoma, experiments so designed were performed in rats and mice. Metabolism of mitom