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Effect of Microgravity on the Pharmacokinetics of Ibuprofen in Humans

✍ Scribed by Idkaidek, Nasir; Arafat, Tawfiq

Book ID
127268902
Publisher
Sage Publications
Year
2011
Tongue
English
Weight
244 KB
Volume
51
Category
Article
ISSN
0091-2700

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Ibuprofen is a chiral drug which is used clinically as a racemate. The pharmacological properties of ibuprofen reside almost exclusively with the S( +)-enantiomer. However, a portion of R( -)-ibuprofen is metabolically inverted to its pharmacologically active, mirror-image form. To investigate the i