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Effect of absorption rate on pharmacokinetics of ibuprofen in relation to chiral inversion in humans

โœ Scribed by Guohua Ding; Yang Liu; Jiewen Sun; Yuriko Takeuchi; Takaki Toda; Toru Hayakawa; Shoji Fukushima; Shuichi Kishimoto; Wenhui Lin; Nobuo Inotsume


Book ID
111770622
Publisher
Pharmaceutical Press
Year
2007
Tongue
English
Weight
297 KB
Volume
59
Category
Article
ISSN
2042-7158

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Effect of propylene glycol on ibuprofen
โœ Christophe Herkenne; Aarti Naik; Yogeshvar N. Kalia; Jonathan Hadgraft; Richard ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 227 KB ๐Ÿ‘ 1 views

The objective was to assess the impact of propylene glycol (PG), a common cosolvent in topical formulations, on the penetration of ibuprofen into human skin in vivo. Drug uptake into the stratum corneum (SC), following application of saturated formulations containing from 0 to 100% v/v PG, was asses