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Effect of metformin on nitric oxide synthase in genetically obese (ob/ob) mice

✍ Scribed by Vijaya B. Kumar; Adonis E. Bernardo; Kamlesh Vyas; Mark Franko; Susan Farr; Lakshmi Lakshmanan; Chakradhar Buddhiraju; John E. Morley

Book ID
117173218
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
338 KB
Volume
69
Category
Article
ISSN
0024-3205

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Effect of metformin on hepatocyte insuli
Effect of metformin on hepatocyte insulin receptor binding in normal, streptozotocin diabetic and genetically obese diabetic (ob/ob) mice
✍ J. M. Lord; T. W. Atkins; C. J. Bailey πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 575 KB

The effect of metformin on hepatocyte insulin receptor binding was examined in normal, streptozotocin diabetic and genetically obese diabetic (ob/ob) mice. In normal mice, chronic administration of metformin (60 mg X kg-1 X day-1 for 50 weeks) increased the number of low affinity receptors by 148%.